BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes

Author:

Tudhope Stephen R.,Cuthbert Nigel J.,Abram Trevor S.,Jennings Michael A.,Maxey Robert J.,Thompson Angela M.,Norman Peter,Gardiner Phillip J.

Publisher

Elsevier BV

Subject

Pharmacology

Reference26 articles.

1. A new structural analogue antagonist of peptido-leukotrienes. The discovery of BAY x7195;Abram;Bioorg. Med. Chem. Letts.,1993

2. Some quantitative uses of drug antagonists;Arunlakshana;Br. J. Pharmacol. Chemother.,1959

3. Pharmacological evidence that human intralobar airways do not contain different receptors that mediate contractions to leukotriene C4 and leukotriene D4;Buckner;J. Pharmacol. Exp. Ther.,1986

4. The role of leukotriene antagonists and inhibitors in the treatment of airway disease;Busse;Am. Rev. Resp. Dis.,1991

5. Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction;Cheng;Biochem. Pharmacol.,1973

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