Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys

Author:

Taylor Jane R.,Lawrence Matthew S.,Redmond D.Eugene,Elsworth John D.,Roth Robert H.,Nichols David E.,Mailman Richard B.

Publisher

Elsevier BV

Subject

Pharmacology

Reference6 articles.

1. D1/D2 dopamine receptor interactions in the regulation of extrapyramidal motor function: Studies in animal models and parkinsonian patients;Barone;Clin. Neuropharmacol.,1986

2. trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: A highly potent selective dopamine D1 full agonist;Brewster;J. Med. Chem.,1990

3. Darney, K.J., M.H. Lewis, W.K. Brewster, D.E. Nichols, M.H. Lewis and R.B. Mailman, Behavioral effects in the rat of dihydrexidine, a high potency full efficacy D1 dopamine receptor agonist, Neuropsychopharmacology (in press).

4. Lesions and dopaminergic drugs alter eye blink rate in African green monkeys;Lawrence;Pharmacol. Biochem. Behav.,1991

5. Dihydrexidine, a novel selective high potency full D-1 receptor agonist;Lovenberg;Eur. J. Pharmacol.,1989

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