Characterisation of the dihydrofolate reductase-thymidylate synthetase gene from human malaria parasites highly resistant to pyrimethamine

Author:

Snewin Valerie A.,England Susan M.,Sims Paul F.G.,Hyde John E.

Publisher

Elsevier BV

Subject

Genetics,General Medicine

Reference30 articles.

1. Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene;Bzik,1987

2. Kinetic and molecular properties of the dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant clones of the human malaria parasite Plasmodium falciparum;Chen;Mol. Pharmacol.,1987

3. Separation of large DNA molecules by contour-clamped homogeneous electric fields;Chu;Science,1986

4. Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate resistant Leishmania tropica;Coderre,1983

5. The mechanism of pyrimethamine resistance in Plasmodium falciparum;Dieckmann;Parasitology,1986

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