Secukinumab for the treatment of psoriasis, psoriatic arthritis, and axial spondyloarthritis: Physical and pharmacological properties underlie the observed clinical efficacy and safety

Author:

Kolbinger Frank,Di Padova Franco,Deodhar Atul,Hawkes Jason E.,Huppertz Christine,Kuiper Torsten,McInnes Iain B.,Ritchlin Christopher T.,Rosmarin David,Schett Georg,Carballido José M.,Häusermann Peter,Calonder Claudio,Vogel Beate,Rondeau Jean-Michel,Bruin Gerard

Funder

GlaxoSmithKline

Janssen Pharmaceuticals

Novartis

UCB

Gilead Sciences

Celgene

AstraZeneca

Boehringer Ingelheim

Eli Lilly and Company

Pfizer

Bristol-Myers Squibb

Novartis Pharmaceuticals Corporation

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmacology

Reference128 articles.

1. Bimekizumab, a novel humanized IgG1 antibody that neutralizes both IL-17A and IL-17F;Adams;Frontiers in Immunology,2020

2. Real-world evidence of secukinumab in psoriasis treatment - a meta-analysis of 43 studies;Augustin;Journal of the European Academy of Dermatology and Venereology,2020

3. Secukinumab dosing every two weeks demonstrated superior efficacy compared to dosing every four weeks in psoriasis patients weighing 90 kg or more;Augustin,2020

4. Continued treatment with secukinumab is associated with high retention or regain of response;Augustin;The British Journal of Dermatology,2020

5. Risankizumab, an IL-23 inhibitor, for ankylosing spondylitis: Results of a randomised, double-blind, placebo-controlled, proof-of-concept, dose-finding phase 2 study;Baeten;Annals of the Rheumatic Diseases,2018

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