Biased GPCR signaling: Possible mechanisms and inherent limitations
Author:
Funder
NIH
Cornelius Vanderbilt Endowed Chair (Vanderbilt University)
Publisher
Elsevier BV
Subject
Pharmacology (medical),Pharmacology
Reference148 articles.
1. Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor;Ahn;The Journal of Biological Chemistry,2004
2. Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2;Ahn;The Journal of Biological Chemistry,2004
3. Targeted elimination of G proteins and Arrestins defines their specific contributions to both intensity and duration of G protein-coupled receptor signaling;Alvarez-Curto;The Journal of Biological Chemistry,2016
4. Chapter eight - probing biased signaling in chemokine receptors;Amarandi,2016
5. β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation;Anthony;Molecular and Cellular Biology,2011
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