The hERG potassium channel and hERG screening for drug-induced torsades de pointes
Author:
Publisher
Elsevier BV
Subject
Pharmacology (medical),Pharmacology
Reference251 articles.
1. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia;Abbott;Cell,1999
2. Impact of ancillary subunits on ventricular repolarization;Abbott;J Electrocardiol,2007
3. Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome;Akar;Circulation,2002
4. Does hERG coassemble with a beta subunit? Evidence for roles of MinK and MiRP1;Anantharam;Novartis Found Symp,2005
5. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism;Anderson;Circulation,2006
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