Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched

Author:

Reed Xylena,Cobb Melanie M.,Skinbinski Gaia,Roosen Dorien,Kaganovich Alice,Ding Jinhui,Finkbeiner Steve,Cookson Mark R.

Funder

Michael J Fox Foundation for Parkinson's Research

National Institutes of Health

National Institute on Aging

National Institute of Neurological Disorders and Stroke

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,General Medicine

Reference19 articles.

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3. A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells;Burkhardt;Mol. Cell. Neurosci.,2013

4. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples;Chomczynski;Biotechniques,1993

5. Representing diversity in the dish: using patient-derived in vitro models to recreate the heterogeneity of neurological disease;Ghaffari;Front. Neurosci.,2018

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