Vpx mediated degradation of SAMHD1 has only a very limited effect on lentiviral transduction rate in ex vivo cultured HSPCs-Reference-Cited by-同舟云学术

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Vpx mediated degradation of SAMHD1 has only a very limited effect on lentiviral transduction rate in ex vivo cultured HSPCs

Published:2015-09 Issue:2 Volume:15 Page:271-280
ISSN:1873-5061
Container-title:Stem Cell Research
language:en
Short-container-title:Stem Cell Research

Author:

Li Duo,Schlaepfer Erika,Audigé Annette,Rochat Mary-Aude,Ivic Sandra,Knowlton Caitlin N.,Kim Baek,Keppler Oliver T.,Speck Roberto F.

Funder

University of Zürich

SNF

US National Institute of Health

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,General Medicine

Reference30 articles.

1. Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott–Aldrich syndrome;Aiuti;Science,2013

2. Rational design of HIV-1 fluorescent hydrolysis probes considering phylogenetic variation and probe performance;Althaus;J. Virol. Methods,2010

3. Intracellular nucleotide levels and the control of retroviral infections;Amie;Virology,2013

4. Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor;Amirache;Blood,2014

5. Maximal lentivirus-mediated gene transfer and sustained transgene expression in human hematopoietic primitive cells and their progeny;Amsellem;Mol. Ther.,2002

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1. Enhancing prime editing in hematopoietic stem and progenitor cells by modulating nucleotide metabolism;Nature Biotechnology;2024-05-28

2. Removal of innate immune barriers allows efficient transduction of quiescent human hematopoietic stem cells;Molecular Therapy;2024-01

3. Nucleotide metabolism constrains prime editing in hematopoietic stem and progenitor cells;2023-10-22

4. Host Cell Restriction Factors Blocking Efficient Vector Transduction: Challenges in Lentiviral and Adeno-Associated Vector Based Gene Therapies;Cells;2023-02-24

5. Antiviral immunity and nucleic acid sensing in haematopoietic stem cell gene engineering;Gene Therapy;2020-07-13

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