Mechanical activation of lung epithelial cells through the ion channel Piezo1 activates the metalloproteinases ADAM10 and ADAM17 and promotes growth factor and adhesion molecule release

Author:

Grannemann Caroline,Pabst Alessa,Honert Annika,Schieren Jana,Martin Christian,Hank Sophia,Böll Svenja,Bläsius Katharina,Düsterhöft Stefan,Jahr Holger,Merkel Rudolf,Leube Rudolf,Babendreyer Aaron,Ludwig Andreas

Publisher

Elsevier BV

Subject

Biomaterials,Biomedical Engineering,Bioengineering

Reference69 articles.

1. Mechanobiology in Lung Epithelial Cells: Measurements, Perturbations, and Responses;Waters,2012

2. Recent advances and new opportunities in lung mechanobiology;Tschumperlin;J. Biomech.,2010

3. Biophysical principles of ion-channel-mediated mechanosensory transduction;Cox;Cell Rep.,2019

4. Mechanosensory transduction: focus on ion channels;Martinac,2017

5. Piezos thrive under pressure: mechanically activated ion channels in health and disease;Murthy;Nat. Rev. Mol. Cell Biol.,2017

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