Estimation of agonist affinity, using the slope of the concentration-effect curve: comment on the method of Calderone and Martinotti-Reference-Cited by-同舟云学术

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Estimation of agonist affinity, using the slope of the concentration-effect curve: comment on the method of Calderone and Martinotti

Published:1998-11 Issue:4 Volume:40 Page:241-243
ISSN:1056-8719
Container-title:Journal of Pharmacological and Toxicological Methods
language:en
Short-container-title:Journal of Pharmacological and Toxicological Methods

Author:

Van der Graaf Piet H.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference3 articles.

1. Operational models of pharmacological agonism;Black;Proc R Soc Lond B,1983

2. Black JW, Leff P, Shankley NP, with an appendix by Wood J (1985) An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation. Br J Pharmacol 84:561–571.

3. A simplified empirical approach to evaluate the dissociation constant of a full agonist by the irreversible receptor inactivation method;Calderone;J Pharmacol Toxicol Meth,1998

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