Synthesis of ethyl-(3R,5S)-dihydroxy-6-benzyloxyhexanoates via diastereo- and enantioselective microbial reduction: Cloning and expression of ketoreductase III from Acinetobacter sp. SC 13874

Author:

Goldberg Steven,Guo Zhiwei,Chen Steve,Goswami Animesh,Patel Ramesh N.

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biochemistry,Biotechnology,Bioengineering

Reference18 articles.

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3. Stereoselective reduction of β-ketoesters by Geotrichum candidum;Patel;Enzyme Microb Technol,1992

4. Practical application of recombinant whole-cell biocatalysts for the manufacturing of pharmaceutical intermediates such as chiral alcohols;Matsuyama;Org Process Res Dev,2002

5. Davis S, Christopher G, John H, Gray D, Gruber J, Huisman G, et al. Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives. PCT Int Appl 2004; 168 pp. WO 2004015132, A2 20040219, CAN 140: 198191, AN 2004: 143313.

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