Engineering of l-threonine aldolase for the preparation of 4-(methylsulfonyl)phenylserine, an important intermediate for the synthesis of florfenicol and thiamphenicol

Author:

Liu Zhicheng,Chen Xi,Chen QijiaORCID,Feng Jinhui,Wang Min,Wu Qiaqing,Zhu DunmingORCID

Funder

National Natural Science Foundation of China

Tianjin Municipal Science and Technology Commission

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biochemistry,Biotechnology,Bioengineering

Reference31 articles.

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3. New antibacterial agents. 2-Acylamino-1-(4-hydrocarbonylsulfonylphenyl)-1,3-propanediols and related compounds;Cutler;J. Am. Chem. Soc.,1952

4. T.L. Nagabhushan, 1-Acyl-2-acylamino-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor, U. S. Pat. 4235892 (1980).

5. Improved preparation of β-hydroxy-α-amino acids: direct formation of sulfates by sulfuryl chloride;Alonso;Tetrahedron Asymmetry,2005

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