Characterization of a novel CYP51 from Rhodococcus triatomae and its NADH-ferredoxin reductase-coupled application in lanosterol 14α-demethylation

Author:

Ke Xia,Ding Guan-Jun,Ma Bin-Xiang,Liu Zhi-Qiang,Zhang Jin-Feng,Zheng Yu-Guo

Funder

National Natural Science Foundation of China

Scientific Research Fund of Zhejiang Provincial Education Department

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biochemistry,Bioengineering

Reference49 articles.

1. W.C. Ault, Abner Eisner, T. John Scanlan, Production of lanolin alcohols United States, 1958.

2. Biological transformations of steroidal compounds: a review;Bhatti;Steroids,2012

3. Biosynthesis of cholesterol and other sterols;Nes;Chem. Rev.,2011

4. The mechanism of the acyl-carbon bond cleavage reaction catalyzed by recombinant sterol 14 alpha-demethylase of Candida albicans (other names are: Lanosterol 14 alpha-demethylase, P-450(14DM), and CYP51);Shyadehi;J. Biol. Chem.,1996

5. Sterol 14 alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms;Lepesheva;BBA,2007

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