Optimizing the medium compositions for accumulation of the novel FR-008/Candicidin derivatives CS101 by a mutant of Streptomyces sp. using statistical experimental methods

Author:

Mao Xiangzhao,Shen Yaling,Yang Liang,Chen Shi,Yang Yuping,Yang Jingya,Zhu Hu,Deng Zixin,Wei Dongzhi

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biochemistry,Bioengineering

Reference28 articles.

1. Microbial natural products: alive and well in 1998;Demain;Nat Biotechnol,1998

2. Biosynthesis of bioactive metabolites and its application to the structural studies and production of hybrid compounds;Nakagawa;J Antibiot,1996

3. Studies on Candicidin biogenesis;Liu;J Antibiot,1972

4. Characterization of the hepaene macrolide antibiotic produced by Streptomyces sp. FR-008;Huang;Zhongguo Kangshengsu Zazhi,1999

5. Organizational and mutational analysis of a complete FR-008/Candicidin gene cluster encoding a structurally related polyene complex;Chen;Chem Biol,2003

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