Recent developments in improving signal detection and reducing placebo response in psychiatric clinical trials

Author:

Mallinckrodt Craig H.,Tamura Roy N.,Tanaka Yoko

Publisher

Elsevier BV

Subject

Biological Psychiatry,Psychiatry and Mental health

Reference44 articles.

1. Dose-response relationship of duloxetine in placebo-controlled clinical trials in patients with major depressive disorder;Bech;Psychopharmacology (Berl),2006

2. “Placebo response in major depression and schizophrenia trials: statistical consideration and design strategies”;Chen,2010

3. A randomized, double-blind, placebo-controlled and active comparator trial of pexacerfont, a corticotropin releasing factor receptor-1 antagonist, in the treatment of generalized anxiety disorder;Coric,2008

4. A critical examination of the sensitivity of unidimensional subscales derived from the Hamilton depression rating scale to antidepressant drug effects;Entsuah;Journal of Psychiatric Research,2002

5. The e_ective sample size and a novel small sample degrees of freedom method;Faes;The American Statistician,2009

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