Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activation

Author:

Robertson Ian B.,Rifkin Daniel B.

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology,Immunology and Allergy,Endocrinology, Diabetes and Metabolism

Reference158 articles.

1. Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans;Herpin;Developmental and Comparative Immunology,2004

2. Informatics approaches to understanding TGFbeta pathway regulation;Kahlem;Development,2009

3. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death;Kulkarni;Proceedings of the National Academy of Sciences of the United States of America,1993

4. TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes;Sanford;Development,1997

5. Tgfbeta2−/− Tgfbeta3−/− double knockout mice display severe midline fusion defects and early embryonic lethality;Dunker;Anatomy and Embryology (Berl),2002

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