Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents

Author:

Rashed Faisal Bin,Diaz-Dussan DianaORCID,Mashayekhi FatemehORCID,Macdonald DawnORCID,Nation Patrick NicholasORCID,Yang Xiao-Hong,Sokhi Sargun,Stoica Alexandru Cezar,El-Saidi Hassan,Ricardo Carolynne,Narain RavinORCID,Ismail Ismail HassanORCID,Wiebe Leonard IrvingORCID,Kumar PiyushORCID,Weinfeld MichaelORCID

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

Terry Fox Foundation

Alberta Cancer Foundation

Alberta Innovates

Publisher

Elsevier BV

Subject

Organic Chemistry,Biochemistry,Clinical Biochemistry

Reference71 articles.

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3. The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities;Walsh;Antioxidants Redox Signal.,2014

4. Tumor hypoxia drives immune suppression and immunotherapy resistance;Ai;J. Immunother. Cancer,2015

5. Significance of nitroimidazole compounds and hypoxia‐inducible factor‐1 for imaging tumor hypoxia;Kizaka‐Kondoh;Cancer Sci.,2009

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