Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q-Reference-Cited by-同舟云学术

Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q

Published:2021-10 Issue: Volume:46 Page:102127
ISSN:2213-2317
Container-title:Redox Biology
language:en
Short-container-title:Redox Biology

Author:

Ayer Anita^ORCID,Fazakerley Daniel J.^ORCID,Suarna Cacang,Maghzal Ghassan J.^ORCID,Sheipouri Diba^ORCID,Lee Kevin J.^ORCID,Bradley Michelle C.,Fernández-del-Rio Lucía,Tumanov Sergey^ORCID,Kong Stephanie MY.,van der Veen Jelske N.,Yang Andrian,Ho Joshua W.K.^ORCID,Clarke Steven G.^ORCID,James David E.^ORCID,Dawes Ian W.,Vance Dennis E.,Clarke Catherine F.^ORCID,Jacobs René L.,Stocker Roland^ORCID

Funder

National Science Foundation

Canadian Institutes of Health Research

Australian Research Council

National Health and Medical Research Council

Publisher

Elsevier BV

Subject

Organic Chemistry,Biochemistry,Clinical Biochemistry

Reference56 articles.

1. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis;Bersuker;Nature,2019

2. DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer;Mao;Nature,2021