Synthesis, molecular modeling and biological evaluation of new benzo[4,5]thieno[3,2-b]pyran derivatives as topoisomerase I-DNA binary complex poisons-Reference-Cited by-同舟云学术

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Synthesis, molecular modeling and biological evaluation of new benzo[4,5]thieno[3,2-b]pyran derivatives as topoisomerase I-DNA binary complex poisons

Published:2021-07 Issue: Volume:112 Page:104915
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Ahmed Eman M.,Khalil Nadia A.,Zaher Ashraf F.,Alhamaky Shimaa M.,El-Zoghbi Mona S.

Funder

National Cancer Institute

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference64 articles.

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3. Microtubule dynamics: taking aim at a moving target;Wilson;Chem. Biol.,1995

4. I.V. Magedov, M. Manpadi, M.A. Ogasawara, A.S. Dhawan, S. Rogelj, S.Van slambrouck, W.F.A. Steelant, N.M. Evdokimov, P.Y. Uglinskii, E.M. Elias, E. J. Knee, P.Tongwa, M.Yu. Antipin, A. Kornienko, Structural simplification of bioactive natural products with multicomponent synthesis. 2. antiproliferative and antitubulin activities of pyrano[3,2-c]pyridones and pyrano[3, 2-c]quinolones, J. Med Chem. 51 (2008) 2561–2570.

5. Topoisomerase inhibitors: pharmacology and emerging nanoscale delivery systems;Dehshahri;Pharmacol. Res.,2020

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1. Design, Synthesis, and Anticancer Evaluation of Hemithioindigos via Inhibition of Human Topoisomerases;ChemistrySelect;2023-11-05

2. New benzothienopyran and benzothienopyranopyrimidine derivatives as topoisomerase I inhibitors: Design, synthesis, anticancer screening, apoptosis induction and molecular modeling studies;Bioorganic Chemistry;2023-08

3. Synthesis of benzo[b]thieno[2,3-c]quinolines via palladium-catalyzed ring-closing reaction;Tetrahedron Letters;2023-01

4. Anti-proliferative activities of 4H-pyran derivatives synthesized from benzoylacetone;Bulletin of the Chemical Society of Ethiopia;2022-12-14

5. Design and synthesis of Aza-boeravinone derivatives as potential novel topoisomerase I inhibitors;Bioorganic Chemistry;2022-05

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