Verifying the role of 3-hydroxy of 17-cyclopropylmethyl-4,5α-epoxy-3,14β-dihydroxy-6β-[(4′-pyridyl) carboxamido]morphinan derivatives via their binding affinity and selectivity profiles on opioid receptors-Reference-Cited by-同舟云学术

Verifying the role of 3-hydroxy of 17-cyclopropylmethyl-4,5α-epoxy-3,14β-dihydroxy-6β-[(4′-pyridyl) carboxamido]morphinan derivatives via their binding affinity and selectivity profiles on opioid receptors

Published:2021-04 Issue: Volume:109 Page:104702
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Huang Boshi,Gunta Rama,Wang Huiqun,Li Mengchu,Cao Danni,Mendez Rolando E.,Gillespie James C.,Chen Chongguang,Huang Lan-Hsuan M.,Liu-Chen Lee-Yuan,Selley Dana E.,Zhang Yan

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference56 articles.

1. A brief history of opiates, opioid peptides, and opioid receptors;Brownstein;Proc. Natl. Acad. Sci.,1993

2. Untangling the complexity of opioid receptor function;Valentino;Neuropsychopharmacology,2018

3. Hot topics in opioid pharmacology: mixed and biased opioids;Azzam;Br. J. Anaesth.,2019

4. Application of bivalent bioisostere concept on design and discovery of potent opioid receptor modulators;Ma;J. Med. Chem.,2019

5. Structure selectivity relationship studies of 17-cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-[(4'-pyridyl)carboxa mido]morphinan derivatives toward the development of the mu opioid receptor antagonists;Yuan;Bioorg. Med. Chem. Lett.,2011

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Blocking potential metabolic sites on NAT to improve its safety profile while retaining the pharmacological profile;Bioorganic Chemistry;2024-07

2. NCP, a Dual Kappa and Mu Opioid Receptor Agonist, Is a Potent Analgesic Against Inflammatory Pain without Reinforcing or Aversive Properties;Journal of Pharmacology and Experimental Therapeutics;2024-02-26

3. IUPHAR review: Recent progress in the development of Mu opioid receptor modulators to treat opioid use disorders;Pharmacological Research;2024-01

4. A straightforward trifluoromethylation at the C6 position of morphinane alkaloids, their modification and evaluation of inhibition of the SARS-CoV-2 main protease;Journal of Fluorine Chemistry;2023-10

5. Endogenous opiates and behavior: 2021;Peptides;2023-06