Exploring of tumor-associated carbonic anhydrase isoenzyme IX and XII inhibitory effects and cytotoxicities of the novel N-aryl-1-(4-sulfamoylphenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamides

Author:

Yamali Cem,Inci Gul Halise,Ozli Gulsen,Angeli Andrea,Ballar Kirmizibayrak Petek,Erbaykent Tepedelen Burcu,Sakagami Hiroshi,Bua Silvia,Supuran Claudiu T.

Funder

TÜBİTAK

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference42 articles.

1. Synthesis of benzensulfonamides linked to quinazoline scaffolds as novel carbonic anhydrase inhibitors;El-Azab;Bioorg. Chem.,2019

2. The role of carbonic anhydrase IX in hypoxia control in OSCC;Perez-Sayans;J. Oral Pathol. Med.,2013

3. Cancer drug development of carbonic anhydrase inhibitors beyond the active site;Singh;Molecules,2018

4. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators;Supuran;Nat Rev Drug Discov,2008

5. Differential expression and function of CAIX and CAXII in breast cancer: A comparison between tumorgraft models and cells;Chen;PLoS ONE,2018

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