Design, synthesis and biological evaluation of novel pyrazolopyrimidone derivatives as potent PDE1 inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis and biological evaluation of novel pyrazolopyrimidone derivatives as potent PDE1 inhibitors

Published:2021-09 Issue: Volume:114 Page:105104
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Zhang Bei,Huang Yue,Zhang Si-Rui,Huang Meng-Xing,Zhang Chen,Luo Hai-Bin

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference46 articles.

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2. Advances in targeting cyclic nucleotide phosphodiesterases;Maurice;Nat. Rev. Drug Discov.,2014

3. Erectogenic effect of the selective phosphodiesterase type 5 inhibitor, DA-8159;Oh;Arch. Pharm. Res.,2000

4. Phosphodiesterase 5 inhibitors: current status and potential applications;Rotella;Nat. Rev. Drug Discov.,2002

5. Vardenafil: a review of its use in erectile dysfunction;Keating;Drugs,2003

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1. Opportunities and perspectives of small molecular phosphodiesterase inhibitors in neurodegenerative diseases;European Journal of Medicinal Chemistry;2024-05

2. Advances in targeting Phosphodiesterase 1: From mechanisms to potential therapeutics;European Journal of Medicinal Chemistry;2024-01

3. Synthesis and Activity Evaluation of Vinpocetine-Derived Indole Alkaloids;Molecules;2023-12-19

4. Identification of Novel Quinolin-2(1H)-ones as Phosphodiesterase 1 Inhibitors for the Treatment of Inflammatory Bowel Disease;Journal of Medicinal Chemistry;2023-08-16

5. Discovery of novel phosphodiesterase-1 inhibitors for curing vascular dementia: Suppression of neuroinflammation by blocking NF-κB transcription regulation and activating cAMP/CREB axis;Acta Pharmaceutica Sinica B;2023-03

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