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Chemoenzymatic enantioselective route to get (+) and (−) 4-acetoxy-azetidin-2-one by lipase-catalysed kinetic resolution and their applications

  • Published:2022-03 Issue: Volume:120 Page:105580
  • ISSN:0045-2068
  • Container-title:Bioorganic Chemistry
  • language:en
  • Short-container-title:Bioorganic Chemistry

Author:

Martelli Giulia,Cirillo Martina,Giraldi Valentina,Giacomini Daria

Funder

Emilia-Romagna Region

Critical Infrastructure Resilience Institute, University of Illinois

Ministero dell’Istruzione, dell’Università e della Ricerca

Università di Bologna

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference54 articles.

1. Recent progress in chemistry of β-lactams;Ombito;Mini-Rev. Org. Chem.,2019

2. Contemporary advances in therapeutic portfolio of 2-azetidinones;Kaur;Chem. Biol. Lett.,2020

3. Azetidin-2-ones, synthon for biologically important compounds;Deshmukh;Curr. Med. Chem.,2004

4. β-lactam antibiotics: An overview from a medicinal chemistry perspective;Lima;Europ. J. Medicinal Chemistry,2020

5. Antibacterial and β-lactamase inhibitory activity of monocyclic β-lactams;Decuyper;Med. Res. Rev.,2018

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