Design, synthesis, and biological activity evaluation of a series of novel sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia-Reference-Cited by-同舟云学术

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Design, synthesis, and biological activity evaluation of a series of novel sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia

Published:2021-06 Issue: Volume:111 Page:104849
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Feng Ziying,Chen Aiping,Shi Jing,Zhou Daoguang,Shi Wei,Qiu Qianqian,Liu Xinhong,Huang Wenlong,Li Jieming,Qian Hai,Zhang Wenjie

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference34 articles.

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2. Histone modifications in epigenetic regulation of cancer: Perspectives and achieved progress;Neganova;Semin. Cancer Biol.,2020

3. Bromodomain: an acetyl-lysine binding domain;Zeng;FEBS Lett.,2002

4. Inducible STAT3 NH2 terminal mono-ubiquitination promotes BRD4 complex formation to regulate apoptosis;Ray;Cell. Signal.,2014

5. Novel strategies targeting bromodomain-containing protein 4 (BRD4) for cancer drug discovery;Liang;Eur. J. Med. Chem.,2020

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1. Synthesis, antiproliferative activity and insilco studies of substituted 2-((N-benzyl-5-bromo-2-methoxyphenyl) sulfonamide) glycinamide derivatives;Synthetic Communications;2024-08-06

2. Targeting hematological malignancies with isoxazole derivatives;Drug Discovery Today;2024-08

3. Current Scenario of Pyridine/Quinoline-Sulfonamide Hybrids with Anticancer Potential (A Review);Russian Journal of General Chemistry;2024-04

4. In silico research on new sulfonamide derivatives as BRD4 inhibitors targeting acute myeloid leukemia using various computational techniques including 3D-QSAR, HQSAR, molecular docking, ADME/Tox, and molecular dynamics;Journal of Biomolecular Structure and Dynamics;2023-09-01

5. Bromodomain inhibitors and therapeutic applications;Current Opinion in Chemical Biology;2023-08

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