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Discovery of isoliquiritigenin analogues that reverse acute hepatitis by inhibiting macrophage polarization

  • Published:2021-09 Issue: Volume:114 Page:105043
  • ISSN:0045-2068
  • Container-title:Bioorganic Chemistry
  • language:en
  • Short-container-title:Bioorganic Chemistry

Author:

Yang Junjie,Hu Fanjie,Guo Chengjun,Liang Yuqing,Song Haiying,Cheng Kui

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangzhou Science and Technology Program key projects

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference39 articles.

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2. PAMPs of the Fungal Cell Wall and Mammalian PRRs;Hatinguais;Curr. Top. Microbiol. Immunol,2020

3. Synthesis, structure-activity relationships and preliminary mechanism study of N-benzylideneaniline derivatives as potential TLR2 inhibitors;Cai;Bioorg. Med. Chem.,2018

4. Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on their Agonists and Antagonists;Federico;J. Med. Chem.,2020

5. Erlotinib protects against LPS-induced endotoxicity because TLR4 needs EGFR to signal;De;Proc. Natl. Acad. Sci.,2015
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