Novel Mannich bases of ciprofloxacin with improved physicochemical properties, antibacterial, anticancer activities and caspase-3 mediated apoptosis-Reference-Cited by-同舟云学术

Novel Mannich bases of ciprofloxacin with improved physicochemical properties, antibacterial, anticancer activities and caspase-3 mediated apoptosis

Published:2021-02 Issue: Volume:107 Page:104629
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Abdel-Rahman Islam M.,Mustafa Muhamad,Mohamed Soad A.,Yahia Ramadan,Abdel-Aziz Mohamed,Abuo-Rahma Gamal El-Din A.,Hayallah Alaa M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference45 articles.

1. Synthesis and characterization of N-Mannich based prodrugs of ciprofloxacin and norfloxacin: In vitro anthelmintic and cytotoxic evaluation;Piplani;J. Adv. Res.,2017

2. Current trends and future directions of fluoroquinolones;Mohammed;Curr. Med. Chem.,2019

3. Inhibition of human transitional cell carcinoma in vitro proliferation by fluoroquinolone antibiotics;Seay;J. Urol.,1996

4. The cytotoxic effects of fleroxacin and ciprofloxacin on transitional cell carcinoma in vitro;Ebisuno;Cancer: Interdiscipl. Int. J. Am. Cancer Soc.,1997

5. Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line;Aranha;Clin. Cancer Res.,2000

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Current Pharmaceutical Research on the Significant Pharmacophore Mannich bases in Drug Design;Current Topics in Medicinal Chemistry;2023-10

2. Assessing the Antiproliferative Potential of a Novel Combretastatin A4 Derivative via Modulating Apoptosis, MAPK/ERK and PI3K/AKT Pathways in Human Breast Cancer Cells;Frontiers in Bioscience-Landmark;2023-08-28

3. N-Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents;ACS Omega;2023-05-18

4. Recent advances in biological applications of mannich bases — An overview;International Journal of Pharmaceutical Chemistry and Analysis;2023-04-15

5. In Vitro Anticancer Activity of Novel Ciprofloxacin Mannich Base in Lung Adenocarcinoma and High-Grade Serous Ovarian Cancer Cell Lines via Attenuating MAPK Signaling Pathway;Molecules;2023-01-23