Flavone inspired discovery of benzylidenebenzofuran-3(2H)-ones (aurones) as potent inhibitors of human protein kinase CK2

Author:

Protopopov M.V.,Vdovin V.S.,Starosyla S.A.,Borysenko I.P.,Prykhod'ko A.O.,Lukashov S.S.,Bilokin Y.V.,Bdzhola V.G.,Yarmoluk S.M.

Funder

National Academy of Sciences of Ukraine

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference52 articles.

1. One-thousand-and-one substrates of protein kinase CK2?;Meggio;FASEB J.,2003

2. Addiction to protein kinase CK2: A common denominator of diverse cancer cells?;Ruzzene;Biochim. Biophys. Acta – Proteins Proteomics,1804

3. Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung;Daya-Makin;Cancer Res.,1994

4. Asymmetric expression of protein kinase CK2 subunits in human kidney tumors;Stalter;Biochem. Biophys. Res. Commun.,1994

5. Antisense oligonucleotides against protein kinase CK2-α inhibit growth of squamous cell carcinoma of the head and neck in vitro;Faust;Head Neck,2000

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