Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activators-Reference-Cited by-同舟云学术

Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activators

Published:2021-03 Issue: Volume:108 Page:104614
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Jo Jeyun,Ibrahim Lara,Iaconelli Jonathan,Kwak Jinsook,Kumar Manoj,Jung Yunjin,Lairson Luke L.,Chatterjee Arnab K.,Schultz Peter G.,Bollong Michael J.,Yun Hwayoung

Funder

National Research Foundation of Korea

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

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1. Optimization of 3-aminotetrahydrothiophene 1,1-dioxides with improved potency and efficacy as non-electrophilic antioxidant response element (ARE) activators;Bioorganic & Medicinal Chemistry Letters;2023-06

2. S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling;Proceedings of the National Academy of Sciences;2023-05-08

3. Terazosin Analogs Targeting Pgk1 as Neuroprotective Agents: Design, Synthesis, and Evaluation;Frontiers in Chemistry;2022-07-26

4. Nrf2/Keap1/ARE signaling: Towards specific regulation;Life Sciences;2022-02

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