Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors-Reference-Cited by-同舟云学术

Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors

Published:2020-09 Issue: Volume:102 Page:104003
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Chetter Ben A.,Kyriakis Efthimios,Barr Daniel,Karra Aikaterini G.,Katsidou Elisabeth,Koulas Symeon M.,Skamnaki Vassiliki T.,Snape Timothy J.,Psarra Anna-Maria G.,Leonidas Demetres D.,Hayes Joseph M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

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