Structure-activity relationship studies of dipeptide-based hepsin inhibitors with Arg bioisosteres

Author:

Kwon Hongmok,Ha Hyunsoo,Jeon Hayoung,Jang Jaebong,Son Sang-Hyun,Lee Kiho,Park Song-Kyu,Byun Youngjoo

Funder

National Research Foundation of Korea

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference66 articles.

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3. Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers;Herter;Biochem. J.,2005

4. Activation of hepatocyte growth factor/scatter factor in colorectal carcinoma;Kataoka;Cancer Res.,2000

5. Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease;Lee;J. Biol. Chem.,2000

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