Design and synthesis of novel isatin-based derivatives targeting cell cycle checkpoint pathways as potential anticancer agents

Author:

Yousef Mohamed A.,Ali Ahmed M.,El-Sayed Wael M.,Qayed Wesam S.,Farag Hassan H.A.,Aboul-Fadl Tarek

Funder

Alexander von Humboldt Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference44 articles.

1. Isatin and its derivatives: a survey of recent syntheses, reactions, and applications;Varun;Med. Chem. Comm.,2019

2. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Bray;CA: A Cancer J. Clin.,2018

3. Regio and stereoselective synthesis of anticancer spirooxindolopyrrolidine embedded piperidone heterocyclic hybrids derived from one-pot cascade protocol;Arumugam;Chem Cent J.,2018

4. Cell Cycle-Targeted Cancer Therapies;Sherr;Annu. Rev. Cancer Biol.,2017

5. Cell cycle regulation by checkpoints;Barnum,2014

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