Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives

Author:

Munir Abida,Khushal Adil,Saeed Kiran,Sadiq Abdul,Ullah Rahim,Ali Gowhar,Ashraf Zaman,Ullah Mughal Ehsan,Saeed Jan Muhammad,Rashid Umer,Hussain Izhar,Mumtaz Amara

Funder

Higher Education Commission

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference34 articles.

1. M.S. Jan, S. Ahmad, F. Hussain, A. Ahmad, F. Mahmood, U. Rashid, O.ur R. Abid, F. Ullah, M. Ayaz, A. Sadiq, Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents, Eur. J. Med. Chem. 186 (2020) 111863.

2. Design, synthesis and biological evaluation of novel ferrocene pyrazole derivatives containing nitric oxide donors as COX-2 inhibitors for cancer therapy;Ren;Eur. J. Med. Chem.,2018

3. New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Design, synthesis, biological activity and structure-activity relationships;Ribeiro;Bioorg. Chem.,2019

4. Novel aryl carboximidamide and 3-aryl-1,2,4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies;Youssif;Bioorg. Chem.,2019

5. New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation;Ahmed;Bioorg. Chem.,2020

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