Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα-Reference-Cited by-同舟云学术

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Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα

Published:2020-06 Issue: Volume:99 Page:103828
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Loboda Kaja Bergant,Valjavec Katja,Štampar Martina,Wolber Gerhard,Žegura Bojana,Filipič Metka,Dolenc Marija Sollner,Perdih Andrej

Funder

Ministry of Education, Science and Sport of the Republic of Slovenia

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference72 articles.

1. National Cancer Institute, https://www.cancer.gov/about-cancer/understanding/statistics (accessed 5. 1. 2020).

2. The hallmarks of cancer;Hanahan;Cell,2000

3. Hallmarks of cancer: the next generation;Hanahan;Cell,2011

4. DNA topology: Topoisomerases keep it simple;Bates;Curr. Biol.,1997

5. Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases;Corbett;Annu. Rev. Biophys. Biomol. Struct.,2004

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1. Design and synthesis of new 1,2,4-oxadiazole/quinazoline-4-one hybrids with antiproliferative activity as multitargeted inhibitors;Frontiers in Chemistry;2024-08-30

2. Molecular choreography: Unveiling the dynamic landscape of type IIA DNA topoisomerases before T-segment passage through all-atom simulations;International Journal of Biological Macromolecules;2024-06

3. Nature-inspired substituted 3-(imidazol-2-yl) morpholines targeting human topoisomerase IIα: Dynophore-derived discovery;Biomedicine & Pharmacotherapy;2024-06

4. N-(benzazol-2-yl)-2-substituted phenylacetamide derivatives: Design, synthesis and biological evaluation against MCF7 breast cancer cell line;Journal of Molecular Structure;2023-08

5. Phenotypic Discovery of Thiocarbohydrazone with Anticancer Properties and Catalytic Inhibition of Human DNA Topoisomerase IIα;Pharmaceuticals;2023-02-23

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