Multi-target rational design and synthesis of novel diphenyl-tethered pyrazolopyrimidines targeting EGFR and topoisomerase II with potential DNA intercalation and apoptosis induction-Reference-Cited by-同舟云学术

Multi-target rational design and synthesis of novel diphenyl-tethered pyrazolopyrimidines targeting EGFR and topoisomerase II with potential DNA intercalation and apoptosis induction

Published:2024-04 Issue: Volume:145 Page:107223
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Gaber Ahmed A,Abo Elmaaty Ayman,Sharaky Marwa,Mosa Aliaa A.,Yahya Abdullah Alzahrani Abdullah,Shaaban Saad,Eldehna Wagdy M.,Al-Karmalawy Ahmed A.

Funder

Deanship of Scientific Research, King Khalid University

Publisher

Elsevier BV

Reference62 articles.

1. The global challenge of cancer

2. Advancing Cancer Therapy

3. Global cancer statistics, 2012;Torre;CA: J. Clin.,2015

4. A compendium of mutational cancer driver genes;Martínez-Jiménez;Nat. Rev. Cancer,2020

5. Cellular senescence promotes adverse effects of chemotherapy and cancer relapsecellular senescence and chemotherapy;Demaria;Cancer Discov.,2017

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Spectroscopic, biological activity, molecular docking and hydrogen storage studies of tetrazole-thione complexes;Journal of Molecular Structure;2024-09

2. Organoselenium-based Azomethines as Apoptosis Inducers in Colorectal Carcinoma via P53, BAX, Caspase-3, Caspase-6, and Caspase-9 Modulations;Current Medicinal Chemistry;2024-08-12

3. Pharmacophore‐based, rationale design, and efficient synthesis of novel tetrahydrobenzo[b]thiophene candidates as potential dual Topo I/II inhibitors and DNA intercalators;Archiv der Pharmazie;2024-06-12