Design, synthesis and biological evaluation of novel quinazoline-derived EGFR/HER-2 dual-target inhibitors bearing a heterocyclic-containing tail as potential anti-tumor agents
Author:
Funder
National Natural Science Foundation of China
Department of Science and Technology of Liaoning Province
Publisher
Elsevier BV
Reference40 articles.
1. Cell signaling by receptor tyrosine kinases;Lemmon;Cell,2010
2. Structure and clinical relevance of the epidermal growth factor receptor in human cancer;Kumar;J. Clin. Oncol.,2008
3. ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency;Lane;Mol. Cell. Biol.,2000
4. The choice of systemic adjuvant therapy in receptor-positive early breast cancer;Dellapasqua;Eur. J. Cancer,2005
5. HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation;Takezawa;Cancer Discov.,2012
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3