Stereospecificity of hydride transfer in NAD+-catalyzed 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry
Reference22 articles.
1. Biosynthesis of aminocyclitol antibiotics.
2. K.L. Rinehart Jr., T. Suami (Eds.), Aminocyclitol Antibiotics, ACS Symposium Series No. 125. American Chemical Society, Washington DC, 1980
3. Stereochemistry of ribostamycin biosynthesis. Application of hydrogen-2 NMR spectroscopy
4. Mechanism and stereochemistry of the biosynthesis of 2-deoxystreptamine and neosamine C.
5. Enzymic carbocycle formation in microbial secondary metabolism. The mechanism of the 2-deoxy-scyllo-inosose synthase reaction as a crucial step in the 2-deoxystreptamine biosynthesis in Streptomyces fradiae
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2. Enhanced Biosynthesis of 2-Deoxy-scyllo-inosose in Metabolically Engineered Bacillus subtilis Recombinants;Frontiers in Microbiology;2018-09-27
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