Structural modeling of osteoarthritis ADAMTS4 complex with its cognate inhibitory protein TIMP3 and rational derivation of cyclic peptide inhibitors from the complex interface to target ADAMTS4-Reference-Cited by-同舟云学术

Structural modeling of osteoarthritis ADAMTS4 complex with its cognate inhibitory protein TIMP3 and rational derivation of cyclic peptide inhibitors from the complex interface to target ADAMTS4

Published:2018-02 Issue: Volume:76 Page:13-22
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Zhang Wei,Zhong Biao,Zhang Chi,Wang Yukai,Guo Shang,Luo Congfeng,Zhan Yulin

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference45 articles.

1. ADAMTS: a novel family of extracellular matrix proteases

2. The ADAMTS(L) family and human genetic disorders

3. The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family

4. The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation

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