Optimization of the benzamide fragment targeting the S2′ site leads to potent dipeptidyl peptidase-IV inhibitors-Reference-Cited by-同舟云学术

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Optimization of the benzamide fragment targeting the S2′ site leads to potent dipeptidyl peptidase-IV inhibitors

Published:2020-01 Issue: Volume:94 Page:103366
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Deng Xiaoyan,Wang Na,Meng Liuwei,Zhou Siru,Huang Junli,Xing Junhao,He Linhong,Jiang Weizhe,Li Qing

Funder

National Natural Science Foundation of China

Guangxi Province Science Foundation for Youths

Joint Cultivation Base of Innovation & Entrepreneurship for Pharmaceutical Postgraduates

Guangxi First-class Discipline Project for Pharmaceutical Sciences

Training Programs of Innovation and Entrepreneurship for Undergraduates

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference33 articles.

1. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

2. Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

3. Targeting the pancreatic β-cell to treat diabetes

4. Diabetes mellitus—advances and challenges in human β-cell proliferation

5. Current anti-diabetic agents and their molecular targets: A review

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1. Computational approaches for lead compound discovery in dipeptidyl peptidase-4 inhibition using machine learning and molecular dynamics techniques;Computational Biology and Chemistry;2024-10

2. Synthesis of β-Amino Carbonyl 6-(Aminomethyl)- and 6-(Hydroxymethyl)pyrazolopyrimidines for DPP-4 Inhibition Study;Current Medicinal Chemistry;2022-06-14

3. Design, synthesis and evaluation of a series of novel long-acting dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes;Bioorganic Chemistry;2022-06

4. Identification and structure–activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus;European Journal of Medicinal Chemistry;2021-12

5. Enhanced piezoelectric wind-induced vibration energy harvester via the interplay between cylindrical shell and diamond-shaped baffle;Nano Energy;2021-11

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