E-pharmacophore guided discovery of pyrazolo[1,5-c]quinazolines as dual inhibitors of topoisomerase-I and histone deacetylase

Author:

Joshi Gaurav,Kalra Sourav,Yadav Umesh Prasad,Sharma Praveen,Singh Pankaj Kumar,Amrutkar Suyog,Ansari Arshad J.,Kumar Santosh,Sharon Ashoke,Sharma Sadhana,Sawant Devesh M.,Banerjee Uttam C.,Singh Sandeep,Kumar Raj

Funder

CIL, CUPB, India

CSIR, New Delhi

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference59 articles.

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2. DNA Topoisomerases in Cancer Therapy;Andoh,2003

3. DNA topoisomerases in cancer therapy;Lock;Anti-Cancer Drug Des.,1987

4. Etoposide: four decades of development of a topoisomerase II inhibitor;Hande;Eur. J. Cancer,1998

5. Topoisomerase I inhibitors: camptothecins and beyond;Pommier;Nat. Rev. Cancer,2006

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