Fine-tuning the properties of the thrombin binding aptamer through cyclization: Effect of the 5′-3′ connecting linker on the aptamer stability and anticoagulant activity-Reference-Cited by-同舟云学术

Fine-tuning the properties of the thrombin binding aptamer through cyclization: Effect of the 5′-3′ connecting linker on the aptamer stability and anticoagulant activity

Published:2020-01 Issue: Volume:94 Page:103379
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Riccardi Claudia,Meyer Albert,Vasseur Jean-Jacques,Russo Krauss Irene,Paduano Luigi,Morvan François,Montesarchio Daniela

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference73 articles.

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2. Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer;Musumeci;Pharmacol. Ther.,2012

3. G-quadruplex aptamers to human thrombin versus other direct thrombin inhibitors: the focus on mechanism of action and drug efficiency as anticoagulants;Zavyalova;Curr. Med. Chem.,2016

4. G-quadruplex-based aptamers against protein targets in therapy and diagnostics;Platella;BBA Gen. Subj.,1861

5. Direct thrombin inhibitors – a survey of recent developments;Schwienhorst;Cell. Mol. Life Sci.,2006

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