Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry
Reference50 articles.
1. Why do so many clinical trials of therapies for Alzheimer's disease fail?;Anderson;Lancet,2017
2. The worldwide economic impact of dementia 2010;Wimo;Alzheimers Dement.,2013
3. Have there been improvements in Alzheimer's disease drug discovery over the past 5 years?;Cacabelos;Expert Opin. Drug Discov.,2018
4. Treatment of Alzheimer's disease: the legacy of the cholinergic hypothesis, neuroplasticity, and future directions;Ashford;J. Alzheimers Dis.,2015
5. Amyloid deposition as the central event in the aetiology of Alzheimer's disease;Hardy;Trends Pharmacol. Sci.,1991
Cited by 81 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Evaluation of 3,4-diethoxy substituted thioureas and their thiazole derivatives as potent anti-Alzheimer's agents: Synthesis, DFT, biological activity and molecular modeling investigations;Journal of Molecular Structure;2024-10
2. Recent advances in Alzheimer’s disease: mechanisms, clinical trials and new drug development strategies;Signal Transduction and Targeted Therapy;2024-08-23
3. Pristine 2-chloroquinoline-based-thiosemicarbazones as multitarget agents against alzheimer's disease: In vitro and in silico studies of monoamine oxidase (MAO) and cholinesterase (ChE) inhibitors;Journal of Molecular Structure;2024-06
4. Synthesis of novel coumarin-triazole hybrids and first evaluation of the 4-phenyl substituted hybrid loaded PLGA nanoparticles delivery system to the anticancer activity;Nanotechnology;2024-05-07
5. Design, synthesis, and biological evaluation of novel capsaicin-tacrine hybrids as multi-target agents for the treatment of Alzheimer's disease;Bioorganic Chemistry;2024-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3