Design, synthesis, crystal structures and anticancer activity of 4-substituted quinolines to target PDK1
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry
Reference31 articles.
1. Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety;Sansook;Org. Biomol. Chem.,2017
2. Serine/threonine kinase 3-phosphoinositide-dependent protein kinase-1 (PDK1) as a key regulator of cell migration and cancer dissemination;Di Blasio;Cancers (Basel),2017
3. 3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer;Fyffe;Cancer Manag. Res.,2013
4. 3-Phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but akt-independent manner;Armando Gagliardi;Neoplasia,2012
5. Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth;Hann;Mol. Cancer.,2014
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