Isoindolin-1-one derivatives as urease inhibitors: Design, synthesis, biological evaluation, molecular docking and in-silico ADME evaluation
Author:
Funder
National Institute for Medical Research Development
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry
Reference131 articles.
1. Jack bean urease (EC 3.5.1.5). Metalloenzyme. Simple biological role for nickel;Dixon;J. Am. Chem. Soc.,1975
2. Nonredox nickel enzymes;Maroney;Chem. Rev.,2014
3. Facile one-pot four-component synthesis of 3,4-dihydro-2-pyridone derivatives: novel urease inhibitor scaffold;Modarres Hakimi;Res. Pharm. Sci.,2017
4. Helicobacter pylori;Dunn;Clin. Microbiol. Rev.,1997
5. Microbial ureases: significance, regulation, and molecular characterization;Mobley;Microbiol. Rev.,1989
Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Photoredox Synthesis of Silicon-Containing Isoindolin-1-ones and Deuterated Analogues Through Hydrosilylation and Deuterium-silylation;The Journal of Organic Chemistry;2024-05-10
2. Metal‐Free K2S2O8 Mediated Synthesis of 3‐(Substituted)‐2‐Arylisoindolin‐1‐One Derivatives With Cascade C−N/C−C Bond Formations Via Radical Cyclization;European Journal of Organic Chemistry;2024-04-17
3. Catalyst-free regioselective synthesis of fused 11H-benzo[5,6][1,4]thiazino[3,4-a]isoindol-11-ones and benzo[b]indeno[1,2-e][1,4]thiazin-11(10aH)-ones targeting bacterial and fungal microbes;Journal of Molecular Structure;2024-04
4. Photoredox-catalyzed C(sp2)–H trifluoromethylation of 3-methylene-isoindolin-1-ones under metal-free conditions;Organic & Biomolecular Chemistry;2024
5. Synthesis, Biological Activity Evaluation, Docking and Molecular Dynamics Studies of New Triazole‐Tetrahydropyrimidinone(thione) Hybrid Scaffolds as Urease Inhibitors;Chemistry & Biodiversity;2023-04-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3