Design, synthesis, anti-inflammatory antitumor activities, molecular modeling and molecular dynamics simulations of potential naprosyn® analogs as COX-1 and/or COX-2 inhibitors

Author:

El Sayed Mardia T.,El-Sharief Marwa A.M.Sh.,Zarie Eman S.,Morsy Nesrin M.,Elsheakh Ahmed R.,Nayel Mohammed,Voronkov Andrey,Berishvili Vladimir,Sabry Nermien M.,Hassan Ghada S.,Abdel-Aziz Hatem A.

Funder

National Research Centre, Applied Organic Chemistry Department

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference37 articles.

1. Large-scale synthetic process for (S)-naproxen by Syntex;Harrington;Org. Process Res. Dev.,1997

2. Human pharmacology of naproxen sodium;Capone;J. Pharmacol. Exp. Therapeut.,2007

3. Gastrointestinal mucosal injury following repeated daily oral administration of conventional formulations of indometacin and other non-steroidal anti-inflammatory drugs to pigs: a model for human gastrointestinal disease;Rainsford;J. Pharm. Pharmacol.,2003

4. The cardiovascular pharmacology of nonsteroidal anti-inflammatory drugs;Grosser;Trends Pharmacol. Sci.,2017

5. The risk of major NSAID toxicity with celecoxib, ibuprofen, or naproxen: a secondary analysis of the PRECISION trial;Solomon;Am. J. Med.,2017

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