Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids-Reference-Cited by-同舟云学术

Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids

Published:2023-02 Issue: Volume:131 Page:106286
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Roleira Fernanda M.F.,Costa Saul C.,Gomes Ana R.,Varela Carla L.,Amaral Cristina,Augusto Tiago V.,Correia-da-Silva Georgina,Romeo Isabella,Costa Giosuè,Alcaro Stefano,Teixeira Natércia,Tavares-da-Silva Elisiário J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference48 articles.

1. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Sung;CA Cancer J. Clin.,2021

2. Clinical review on the management of hormone receptor-positive metastatic breast cancer;Mcandrew;JCO Oncol. Pract.,2021

3. The potency and clinical efficacy of aromatase inhibitors across the breast cancer continuum;Lønning;Ann. Oncol.,2011

4. Long-term management of patients with hormone receptor-positive metastatic breast cancer: concepts for sequential and combination endocrine-based therapies;Brufsky;Cancer Treat. Rev.,2017

5. Toxicity of extended adjuvant endocrine with aromatase inhibitors in patients with postmenopausal breast cancer: a systemtic review and meta-analysis;Zhao;Crit. Rev. Oncol. Hematol.,2020

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Aromatase inhibitors for the treatment of breast cancer: An overview (2019–2023);Bioorganic Chemistry;2024-10

2. Steroidal epoxides as anticancer agents in lung, prostate and breast cancers: The case of 1,2-epoxysteroids;Biochemical Pharmacology;2024-07

3. Synthesis and biological activity of 11-Oxygenated and heterocyclic estrone analogs in pancreatic cancer monolayers and 3D spheroids;Bioorganic & Medicinal Chemistry;2024-04

4. Aromatase Inhibitors as a Promising Direction for the Search for New Anticancer Drugs;Molecules;2024-01-10

5. A novel and easy protocol to obtain 6-alkoxy-Δ4,6-diene-3-one derivatives from available sterols;Steroids;2023-12