Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold-Reference-Cited by-同舟云学术

Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold

Published:2022-06 Issue: Volume:123 Page:105768
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Lu Haibo,Lu Tian,Zu Shijia,Duan Zhe,Guang Yiman,Li Qi,Ma Jingyi,Chen Dongying,Li Bo,Lu Wenchao,Jiang Hualiang,Luo Cheng,Ye Deyong,Chen Kaixian,Lin Hua

Funder

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

Fujian Normal University

State Key Laboratory of Drug Research

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

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1. Bromodomain inhibitors and therapeutic applications;Current Opinion in Chemical Biology;2023-08

2. Design of Class I/IV Bromodomain-Targeting Degraders for Chromatin Remodeling Complexes;ACS Chemical Biology;2023-06-01

3. Discovery of CECR2 Bromodomain Inhibitors with High Selectivities over BPTF Bromodomain;Chinese Journal of Chemistry;2022-06-21