Synthesis, biological evaluation and docking studies of methylene bearing cyanopyrimidine derivatives possessing a hydrazone moiety as potent Lysine specific demethylase-1 (LSD1) inhibitors: A promising anticancer agents-Reference-Cited by-同舟云学术

Synthesis, biological evaluation and docking studies of methylene bearing cyanopyrimidine derivatives possessing a hydrazone moiety as potent Lysine specific demethylase-1 (LSD1) inhibitors: A promising anticancer agents

Published:2022-09 Issue: Volume:126 Page:105885
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Tasneem Sharba,Sheikh Khursheed A.,Naematullah Md,Mumtaz Alam M.,Khan Farah,Garg Manika,Amir Mohd.,Akhter Mymoona,Amin Shaista,Haque Anzarul,Shaquiquzzaman Mohammad^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference64 articles.

1. R.L. Siegel, K.D. Miller, H.E. Fuchs, A. Jemal, Cancer statistics, 2021. CA: Cancer J. Clin. 71 (2021) 7-33. DOI: https://doi.org/10.3322/caac.21654.

2. H. Sung, J. Ferlay, R.L. Siegel, M. Laversanne, I. Soerjomataram, A. Jemal, F. Bray, Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA: Cancer J. Clin. 71 (2021) 209-249. DOI: https://doi.org/10.3322/caac.21660.

3. Rational design and latest advances of codelivery systems for cancer therapy;Meng;Materials Today Bio,2020

4. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1;Shi;Cell.,2004

5. LSD1: Oxidative chemistry for multifaceted functions in chromatin regulation;Forneris;Trends Biochem. Sci.,2008

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Imidazole-based hydrazones as potent anti-colon cancer agents: Design, synthesis, biological evaluation and computational studies;Journal of Molecular Structure;2024-12

2. Nickel(II) and Palladium(II) complexes with imine-based tridentate ligand: Synthesis, spectral characterization, Antimicrobial, cytotoxicity and DFT studies;Polyhedron;2024-07

3. Hydrazide-hydrazone/hydrazone as enabling linkers in anti-cancer drug discovery: A comprehensive review;Journal of Molecular Structure;2024-07

4. Exploring cyclopropylamine containing cyanopyrimidines as LSD1 inhibitors: Design, synthesis, ADMET, MD analysis and anticancer activity profiling;Bioorganic Chemistry;2024-06

5. Salicylaldehyde-derived piperazine-functionalized hydrazone ligand-based Pt(ii) complexes: inhibition of EZH2-dependent tumorigenesis in pancreatic ductal adenocarcinoma, synergism with PARP inhibitors and enhanced apoptosis;Dalton Transactions;2024