Synthesis of N-benzyl substituted 1,4-imino-l-lyxitols with a basic functional group as selective inhibitors of Golgi α-mannosidase IIb-Reference-Cited by-同舟云学术

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Synthesis of N-benzyl substituted 1,4-imino-l-lyxitols with a basic functional group as selective inhibitors of Golgi α-mannosidase IIb

Published:2019-03 Issue: Volume:83 Page:424-431
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Klunda Tomáš,Šesták Sergej,Kóňa Juraj,Poláková Monika

Funder

Slovak Research and Development Agency, Slovakia

Scientific Grant Agency of the Ministry of Education of Slovak Republic and Slovak Academy of Sciences, Slovakia

ERDF, EU

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference69 articles.

1. Iminosugars: From Synthesis toTherapeutic Applications;Compain,2007

2. Naturally Occurring Iminosugars and Related Compounds: Structure, Distribution, and Biological Activity

3. Nothing in Glycobiology Makes Sense, except in the Light of Evolution

4. Natural and Synthetic Iminosugars as Carbohydrate Processing Enzyme Inhibitors for Cancer Therapy

5. Iminosugar antivirals: the therapeutic sweet spot

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. (5S)-5-Benzylswainsonines as potent and selective inhibitors of Golgi α-mannosidase II: synthesis, enzyme evaluation and molecular modelling;Bioorganic Chemistry;2024-09

2. Golgi α-mannosidase: opposing structures of Drosophila melanogaster and novel human model using molecular dynamics simulations and docking at different pHs;Journal of Biomolecular Structure and Dynamics;2023-05-09

3. Synthesis, α-mannosidase inhibition studies and molecular modeling of 1,4-imino-ᴅ-lyxitols and their C-5-altered N-arylalkyl derivatives;Beilstein Journal of Organic Chemistry;2023-03-06

4. Glycosidase-targeting small molecules for biological and therapeutic applications;Chemical Society Reviews;2023

5. Advances in the Chemistry of (−)‐D‐Swainsonine;ChemistrySelect;2022-07-20

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