Imidazo[2′,1′:2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study-Reference-Cited by-同舟云学术

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Imidazo[2′,1′:2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study

Published:2018-10 Issue: Volume:80 Page:11-23
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Ewida Menna A.,Abou El Ella Dalal A.,Lasheen Deena S.,Ewida Heba A.,El-Gazzar Yomna I.,El-Subbagh Hussein I.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference49 articles.

1. The thymidylate synthesis cycle and anticancer drugs

2. The renewed potential for folate antagonists in contemporary cancer chemotherapy

3. Synthesis and Biological Activities of Conformationally Restricted, Tricyclic Nonclassical Antifolates as Inhibitors of Dihydrofolate Reductases

4. Improved survival with highly active antiretroviral therapy in HIV-infected patients with severe Pneumocystis carinii pneumonia

5. Antimycobacterial Activities of 2,4-Diamino-5-Deazapteridine Derivatives and Effects on Mycobacterial Dihydrofolate Reductase

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1. An overview of pyridazin-3(2 H )-one: a core for developing bioactive agents targeting cardiovascular diseases and cancer;Future Medicinal Chemistry;2024-08-06

2. Dihydrofolate Reductase (DHFR) Inhibitors: A Comprehensive Review;Current Medicinal Chemistry;2024-02

3. Transition‐metal‐free Cyclization of Mucohalic Acids with Sulfonyl Hydrazides: An Approach to Pyridazin‐3(2H)‐ones;Asian Journal of Organic Chemistry;2023-09-27

4. A Review on the Synthesis and Anticancer Potentials of Imidazothiazole Derivatives;Mini-Reviews in Medicinal Chemistry;2023-09

5. 2-Amino-1,3-benzothiazole: Endo N-Alkylation with α-Iodo Methyl Ketones Followed by Cyclization;Molecules;2023-02-23

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