Design, synthesis and evaluation of EZH2-based PROTACs targeting PRC2 complex in lymphoma-Reference-Cited by-同舟云学术

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Design, synthesis and evaluation of EZH2-based PROTACs targeting PRC2 complex in lymphoma

Published:2023-11 Issue: Volume:140 Page:106762
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Xie Huiru,Xu Wei,Liang Jing,Liu Yang,Zhuo Chenxi,Zou Xiaoxue,Luo Weihong,Xiao Jianping,Lin Yu,Chen Lixia,Li Hua

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference29 articles.

1. Role of histone H3 lysine 27 methylation in polycomb-group silencing;Cao;Science,2002

2. The EZH2 polycomb transcriptional repressor—a marker or mover of metastatic prostate cancer?;Sellers;Cancer Cell,2002

3. EZH2: a novel target for cancer treatment;Duan;J. Hematol. Oncol.,2020

4. Histone methyltransferase activity of a drosophila polycomb group repressor complex;Müller;Cell,2002

5. Targeting EZH2 in cancer therapy;Yamagishi;Curr. Opin. Oncol.,2017

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Expanding the ligand spaces for E3 ligases for the design of protein degraders;Bioorganic & Medicinal Chemistry;2024-05

2. Regulation of EZH2 protein stability: new mechanisms, roles in tumorigenesis, and roads to the clinic;eBioMedicine;2024-02

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